Ethyl Chloroformate (ECF)

Ethyl Chloroformate (ECF)

Ethyl Chloroformate (ECF) is a reactive organic chemical primarily used as a reagent in pharmaceutical and fine chemical synthesis. It serves as a key intermediate for the preparation of chloroformates, carbonates, carbamates, and amino acid derivatives. Due to its strong reactivity, ECF is widely used in peptide synthesis, agrochemical production, and specialty chemicals.

Product Specifications

• Chemical Name: Ethyl Chloroformate
• CAS Number: 541-41-3
• Molecular Formula: C₃H₅ClO₂
• Molecular Weight: 108.52 g/mol
• Appearance: Colorless to pale yellow liquid
• Purity: ≥ 99%
• Boiling Point: 94 °C
• Density: ~1.14 g/cm³
• Packing: Sealed drums / HDPE containers

Applications

• Pharmaceutical synthesis reagent
• Intermediate in agrochemical manufacturing
• Preparation of chloroformates and carbonates
• Peptide and amino acid derivatization
• Synthesis of carbamates and ureas
• Polymer and specialty chemical intermediates

Key Advantages

• Highly reactive reagent for clean esterification reactions
• Versatile synthetic building block
• Preferred for pharmaceutical and lab-scale organic synthesis

Safety & Handling

Ethyl Chloroformate is corrosive and toxic. Avoid inhalation and direct contact. Handle in a fume hood with appropriate PPE. Refer to SDS for complete safety instructions.

Storage

Store in a cool, dry, and well-ventilated area in tightly sealed containers. Protect from moisture and heat sources.

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